I think what makes Buddhism unique — what makes it Buddhism — is its diagnosis of what causes suffering, which is called the second noble truth.
Looking at the other noble truths, most religions acknowledge the pervasive reality of suffering, that it can end (if not in this life, then after), and that wisdom, compassion, and ethical living are a path to less suffering.
But why do we suffer at all? This is where Buddhism stands alone, offering a real-world explanation that is simple, testable, and, to my mind, irrefutable. What is it like to detox our mind of ego and these three poisons? We already know.
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